Talia had suffered from a form of nerve cancer called neuroblastoma for over seven years but continued to make videos for her fans throughout her battle.
Her family announced the sad news through the Facebook page ‘Angels for Talia’ yesterday, saying: ‘It is with a heavy heart that we share with all of you that Talia has earned her wings at 11:22am.’
The statement continued: ‘We will miss you more than you will ever know baby girl.’
Talia was famed for her appearance on Ellen DeGeneres’ US talk show earlier this year when the inspiring youngster spoke about her talent for makeup and beauty and addressed her brave battle with cancer.
Inspired by her story, the famous host made Talia an honorary ambassador of CoverGirl – the famous American cosmetics company Ellen represents.
The host explained: ‘CoverGirl heard your story and they want to make you an honorary CoverGirl
‘I am inspired by people like yourself. I think there are a lot of people who go through a lot of struggling situations, and despite what the doctors have said and the cancer you're going through, how do you stay so positive?’ she asked.
‘When people ask me that, what do you want me to do, be depressed? I mean a little fishy told me, “Just keep swimming, just keep swimming!”’ Talia responded, referring to Ellen's character Dory in Finding Nemo.
Ellen added: ‘You are really quite something. There's a depth to your soul that is not a 13-year-old soul’
‘You're an old soul and you are very special and amazing, and I'm so honored that you wanted to meet me and that I got to meet you.’
Yesterday, the famous host and comedian took to Twitter to express her condolences for Talia’s family, writing: ‘This year I met a very special girl, and today we lost her. Sending my heart to Talia's family.’
‘I'm so sad,’ she added.
A spokesperson from CoverGirl also said Talia had ‘showed us what true beauty means.’