Madeleine McCann was three-years-old when she disappeared from her bed in a holiday apartment in Portugal in May 2007.
Ever since then, her parents have campaigned tirelessly for information as to their little girl’s whereabouts.
Tragically, they are still no closer to finding out where Madeleine is - or what happened that fateful night in Praia Da Luz.
This will be the McCann’s ninth Christmas without Madeleine.
As a result, Gerry and Kate McCann are supporting Missing People's Christmas campaign, which features 12 families who are missing a parent, sibling, son or daughter.
And, in order to raise awareness, they have released a list of the 22 things they miss most about their little girl.
Kate & Gerry McCann’s list of things they miss most about Madeleine:
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Her smile.
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Her laughter.
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Her eyes.
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Her dimples.
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Her sense of humour.
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Her smartness.
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Her imitations of people and characters.
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Her voice, her ‘chat’.
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Her company.
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That knowing look.
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Her singing.
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Styling her hair.
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Chasing her round the garden.
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Sharing her excitement in the run-up to Christmas.
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Sharing anything.
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Spoiling her on her birthday.
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Shopping with her.
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Going to a cafe with her.
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Holding her, hugging her, kissing the top of her head.
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Lying next to her.
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Our complete family of five.
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Everything.
They added simply: “We miss her.”
Missing People chief executive Jo Youle said: "For the families of missing people, the thought of Christmas without their loved one is heart-breaking.
"This exhibition will give the public the opportunity to stand with these families missing a loved one, by sharing messages of hope and supporting our annual Home for Christmas Appeal so Missing People can continue to be a lifeline when someone disappears."
The exhibition will open on 14 October and be displayed until 22 November at The Crypt, St-Martin-in-the-Fields, Trafalgar Square.