Dr Christian: Do antidepressants really work?

GP & TV presenter Dr Christian Jessen answers your health questions.


by Closer staff |
Published on

My GP started me on antidepressants last week, but I don’t feel they are working. Should I go back? Anna, by email

Antidepressants take around two to four weeks to take enough effect for you to start to notice an improvement. They increase the levels of the chemicals in your brain called neurotransmitters – which transmit messages between brain cells and are thought to have an important effect on your mood. Levels of neurotransmitters rise gradually, so most people will need to take antidepressants for a few weeks before they start to work. It’s important to continue to take the dose your GP recommended and give them time to work properly. They may be more effective in conjunction with psychotherapy, so it might be worth asking your GP about this, too.

Side effects of antidepressants can include drowsiness, blurred vision, disturbed sleep, nausea and either feeling hungry or a loss of appetite. The longer you are on the medication, the more used to it you should get, and so side effects tend to improve. Never just stop taking your pills, even if you think you’re feeling better. Doing so can cause dizziness, vivid dreams and other unpleasant symptoms. Antidepressants are usually stopped by reducing the dose gradually. If you feel you are not coping well, please talk to your GP – you’re not alone.

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