The couple – who have been married for 15 years – are said to be living apart.
According to Radar Online, Jada, 42, has now moved into brother Caleeb’s LA home while Will, 45, is reportedly living in New Orleans while filming his latest movie.
It comes after Jada reportedly told the audience at a charity event: ‘When you are going through a storm with your spouse... stop thinking about what you “believe” a husband or wife should be.’
'Things seemed tense for months’
A source close to the actors – who have not been pictured together since August - said: ‘They were considered to have one of the most solid marriages in Hollywood, but lately it hasn’t seemed that way. Things seemed tense for months.’
It has long been speculated that the couple have an open marriage, with Jada admitting earlier this year that her husband ‘can do whatever he wants.’
She later clarified on Facebook: 'Will and I can both do whatever we want because we trust each other to do so. This does not mean we have an open relationship. It means we have a grown one.'
‘There are more important things to talk about than whether I have an open marriage,’ she added.
In April she responded to relentless reports that she and Will are no longer together by telling Gala magazine: ‘These rumors are completely untrue. I travel a lot because of my work, just like Will does. But our lifestyle hasn’t changed.
‘Before we had the kids, we were already far away from each other quite often because of separate projects.'
She and Will have two children together - Willow, 12, and Jaden, 15.