The 44-year-old broke the news to fans after a meeting with band mates Gary Barlow, Mark Owen and Howard Donald.
He said in an emotional statement: “I want to start by saying how proud I am of what we have achieved together over the years.
"However, at a band meeting last week I confirmed to Mark, Gary and Howard that I do not wish to commit to recording and promoting a new album.
"I have spent some of the best years of my life with Take That and I’d like to thank everyone who has been a part of my journey, including my bandmates, who I feel are like brothers to me.”
He continued: “Most especially my gratitude goes to all of the good and kind, beautiful and ever-loyal fans of the band, without whom none of this could have been possible. Thank you.
"There have been no fallings out, only a decision on my part that I no longer wish to do this.
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"I know how much Mark, Gary and Howard enjoy writing and making music, and they know that they have my full support and encouragement to continue on with what is to be another chapter for the band.”
Following the news, the remaining members of Take That released a statement reading: “This is a sad day for us. Jason leaving is a huge loss both professionally and even more so personally.
"We first became aware of Jason's reservations a couple of years ago but had hoped that by giving him the desired time and space he may begin to feel differently.
"This has not been the case and we now have to accept and fully respect his decision which we know hasn’t been an easy one.
"Jason’s energy and belief in what this band could achieve has made it what it is today, and we’ll forever be grateful for his enthusiasm, dedication and inspiration over the years.”
A source told The Mirror that there was no animosity or tension over the split and Gary, Mark and Howard have all accepted Jason’s decision.
They said: “There was no arguments, no rows about this... just a sense of shock. But they all fully accept Jason’s decision.”
Former Take That member Robbie Williams quit the band in 1995 and the band then 'disbanded' just months later. The members then reunited without Robbie in 2005.
Are you sad by Jason’s departure from Take That?