Earlier in the show, Phil had sucked in his cheeks to reveal impressively-defined cheekbones, prompting one cheeky viewer to add make-up to a picture of his face.
Cue pregnant Holly bursting into giggles and quipping: "You look a bit like Pat St Clement" - much to the amusement of the production crew.
Phillip, however, was less happy about being compared to the legendary EastEnders actress.
After standing with his mouth open for a few minutes, he laughingly told Holly that she could present the rest of the show by herself - and promptly exited the studio.
Watch it for yourself below:
We love how all Holly can say for herself is: "Oh goodness me.... I'm in trouble!"
SEE: PREGNANT HOLLY WILLOUGHBY'S BEST MATERNITY FASHION MOMENTSSEE: PREGNANT HOLLY WILLOUGHBY'S BEST MATERNITY FASHION MOMENTS
Anyone else think that Phillip was just playing around? It's almost guaranteed he and BFF Holly made up minutes later.