The 30-year-old star claimed thinking of gift ideas for one-year-old North was stressing her out.
It was recently rumoured that Kim, 34, and Kanye, 36, had hired a stylist for North, and Khloe told E!: "I'm not going to compete with the clothing for her.
"She is a major fashionista. That stresses me out, the fact that I'm nervous to buy a one-year-old something."
Khloe then admitted she was going to stick toys and "things I know she likes to play with".
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Luckily for Khloe, her other niece and her nephew aren't as tricky to buy for.
Sister Kourtney, 35, and 31-year-old Scott Disick have son Mason, 4, and two-year-old daughter Penelope.
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Khloe revealed little Mason will be getting Teenage Mutant Ninja Turtles toys from her and that Penelope was even easier.
She said: "P just loves baby dolls. She's easy with one baby doll."
And what does Khloe want for Christmas? "What I really love is when people buy me interior things," she added. "Coffee table books. I like that kind of stuff."