A US magazine ran the story that 31-year-old Scott was cheating on long-term partner Kourtney, 35, with her younger half-sister Kendall, 19.
But Khloe, 30, has mocked the rumours. She tweeted: “I’m really pissed about this whole @KendallJenner and @ScottDisick thing!!
“Scott, I thought it was you and I that was having the affair! Scott is such a THOT! These hoes really ain’t loyal!! Huh?!?! Damn Gina!!! Damn!!!”
But luckily Scott was on hand to reassure her. He replied: “Don’t worry @khloekardashian you will always be my number 1.”
A source reportedly told the magazine: “At first, Kourtney was in complete shock and disbelief. But after she processed the information, she was devastated… She started screaming at [Scott], calling him ‘sick’.”
Scott and Kourtney got together in 2006 and have three children: Mason, five, Penelope, two and one-month-old son Reign Aston.
Speaking recently, Scott revealed that he and Kourtney won’t be getting married anytime soon – because they just do not feel the need to.
He told People magazine: “If it’s not broke don’t fix it – we’re happy the way it is.
“I don’t even think we’ll have time to get married at the rate we’re popping out kids.”
Do you believe the affair rumours?