But in a recent interview, Bradley has revealed the path to fame was far from smooth.
Indeed, the 38-year-old heartthrob, went so far as to admit he wanted to 'kill himself' at the beginning of his career, when he felt he was being sidelined on the TV series Alias, on which he played reported Will Tippin.
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'I would only work three days a week. And then for the second season, I got even more sidelines…next thing you know I was like, "I want to f***ing kill myself."'
But the Hangover star admits he also struggled with alcohol addiction, stating 'Yes of course it hindered the work.'
And after getting sober Bradley said he embraced every role he could get his hands on.
'I was doing these movies, and I got to meet Sandra Bullock and meet these people and work with them.'
'And I'm sober and I'm like: "Oh, I'm actually myself."'
He went so far as to say he stopped pretending to be someone else, and rediscovered himself.