Caroline Aherne has been narrating surprise TV hit Gogglebox since it began in 2013.
And, when she confirmed that she had been diagnosed with lung cancer in 2014, she continued to record her voiceovers for the show.
Speaking out after her diagnosis, she said: "I will be narrating this week's Gogglebox, and I will continue to narrate Gogglebox for as long as Gogglebox want me."
Caroline stuck true to her word, taking just one brief break from the show to have hospital treatment for the disease.
Her writing partner, Craig Cash, took over for her at that time - but she soon returned to present the seventh series of the BAFTA award-winning show.
However, over the past two weeks, Caroline has been missing from Gogglebox.
Her continued absence has meant that her old Royle Family co-star Craig Cash has been filling in for her again - something which fans soon picked up on.
It wasn’t long before viewers became worried about the 52-year-old, taking to Twitter to express their concerns.
We would like to point out that there is no reason to suggest Caroline’s condition has anything to do with her absence.
There has been no comment from either her or her publicist - and, as we have previously mentioned, Cash has been filling in for her intermittently since November 2013.
The Gogglebox star (who also found fame in The Mrs Merton Show and The Royle Family) has been busy raising awareness for Macmillan Cancer Support.
She said: "I've had cancer and my brother's had cancer and we know how it affects people."
Caroline then went on to speak at the launch of the Macmillan Cancer Improvement Partnership, a £3.4million scheme to bring together hospitals, GPs, hospices and Manchester city council to co-ordinate cancer care in her home city.
Speaking at the event, she said: “When you hear the doctors say you have cancer, it’s true you really don’t take it in properly.
“You just don’t think of the questions.”