The Gravity actor, 52, has been linked to pretty much every beautiful actress or model out there - with the latest being the beautiful Stacy Keibler and before her model Elisabetta Canalis.
But when asked in an interview with W magazine who the greatest love of his life was, George replied: 'I haven't met her yet.'
So what exactly is the former ER actor looking for in a woman, if such individuals have fallen short?
'When I was a kid, I was in love with Audrey Hepburn...I thought she was as elegant as anything I'd ever seen. And I fell madly in love with her' said the star.
He continued: 'I also always loved Grace Kelly. I mean, when she comes out of the water in To Catch A Thief, I thought, 'That's the most beautiful woman I've ever seen."'
George, who has received critical acclaim for his role in Gravity alongside Sandra Bullock, is well known as a Hollywood lothario, having also dated Renee Zellwegger, Lucy Lui and our very own Lisa Snowdon over the years.
Way to anger all of your ex's at once George...