The soap stars are allegedly feuding over Kym's fiancé Dan Hooper, who is rumoured to be taking a break from.
It was reported this week that Dan's ex Stephanie, 37, was behind the blazing rows between Kym, 38, and Dan that are causing the problems in their relationship.
Now organisers of the soap event, which takes place next Saturday in Manchester, are said to be doing everything they can to keep the women away from each other.
A source told the Mirror: "This night should be all about the drama on-screen rather than between the stars. So organisers will be on high alert.
"Kym has worked really hard on her storyline so she wants the night to be a celebration of that, rather than about problems in her personal life.
"But once the booze starts flowing, who knows what will happen?"
Dan, 32, and Coronation Street star Kym got together in April last year, and confirmed their engagement in December.
Hollyoaks actress Stephanie - who is said to be dating former Apprentice contestant James Hill - has four-old-daughter Lexi-Grace with personal trainer Dan.