So we're unsurprised that the 31-year-old hit back at a negative Instagram user this week, after Rob made a rare appearance on social media.
Rob, 28, shared a video of minister and human rights activist Malcolm X, simply captioned with a few emojis.
Despite this, some took the post to mean Rob was comparing himself to Malcolm – and hit out.
But Khloe was on hand to reign in the keyboard warriors. She fumed: "He's not comparing himself you judgemental f**k. Where did he say he was?!?!
"He's simply admiring another man's wisdom, strength and courage… Can't one admire another without the stones being thrown. Chill out. Get off my brother's page.
"He gets criticised for being too private and then when he decides to get back on social media he gets attacked. Damned if you do and damned if you don't. Let's uplift one another and not assume. Let's all root for Rob."
After almost completely withdrawing from the public eye, after piling on 100lbs and battling with social anxiety, it appears Rob is ready to make his comeback.
As well as his return to social media, it's been reported that he will debut his weight loss on family reality show Keeping Up With The Kardashians.